产品货号:
Z38213
中文名称:
HLA-DPB1抗体
英文名称:
Anti-HLA-DPB1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-HLA-DPB1 Antibody |
指标别名 | DPB1;HLA DP1B;HLA DPB1;HLA-DPB1;MHC class II antigen DPB1 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | WB,IHC,ICC/IF,IP |
基因名称 | HLA-DPB1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthesized peptide derived from human MHC Class II |
实际分子量 | 29KD |
成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
纯化方式 | Affinity-chromatography |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | HLA class II histocompatibility antigen,DP(W2) beta chain is a protein that in humans is encoded by the HLA-DPB1 gene.HLA-DPB belongs to the HLA class II beta chain paralogues.This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB),both anchored in the membrane.It plays a central role in the immune system by presenting peptides derived from extracellular proteins.Class II molecules are expressed in antigen presenting cells (APC:B lymphocytes,dendritic cells,macrophages).The beta chain is approximately 26~28kDa and its gene contains 6 exons.Exon one encodes the leader peptide,exons 2 and 3 encode the two extracellular domains,exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities,resulting in up to 4 different molecules. |
Uniprot ID | P04440 |
基因名全称 | HLA class II histocompatibility antigen,DP beta 1 chain |
推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:20~100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20~100 Immunocoprecipitation 1:20 |
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